Dr Steves said: "We can see that cases have really been coming down in the past week despite New Year celebrations, and now hospitalisation rates look like they might be stabilising, for now at least. Having issues? Cases in people who were fully vaccinated with either Pfizer or Moderna's vaccine, but not boosted, remained mild, but slightly more intense. Almost half of the patients with Omicron symptoms that she treated were not vaccinated. } else { Early data suggests Omicron is spreading in South Africa at a very fast pace as compared to the previous variants. Speaking of the Merck's COVID-19 pill, Molnupiravir, he says, "these are also approved only for patients with mild and moderate symptoms and they come with alot of side effects, so we have to take it with a pinch of salt.". The . The coronavirus, which causes COVID, has been mutating into numerous variants ever s BSc - Food Science & Nutrition, PGD in Sports Nutrition and Dietitics , Diabetes Educator, Translational Nutrigenomics. Given the current scenario, it is critical to be aware of all typical and uncommon signs of a respiratory infection so that action can be taken as soon as possible to avoid any unforeseen . I am a MD physician, and an infectious disease expert speaking from Mumbai. pic.twitter.com/MK9wK8GdwB. Omicron COVID-19 Variant: Senior intensivist at Jaslok Hospital, Dr Pinank Pandya, talks about the Omicron variant, how it's been affecting the patients in the last 2 weeks, what its symptoms are . In a double-blinded, placebo-controlled trial, Paxlovid decreased hospitalization and death 88% when given to unvaccinated, high-risk patients within 5 days of mild to moderate COVID symptoms. Even so, some people with omicron will fall severely ill. A December 2016 study out of London reported that the five most common symptoms appear to be runny nose, headache, fever, fatigue, and sore throat. Causes and Treatment for HIV A very good evening to all of you. RELATED: 90 Percent of People Hospitalized With Omicron Have This in Common. Youve read {{metering-count}} of {{metering-total}} articles this month. Runny nose. The virus has already shaken the world. This is likely a result of the 30 point mutations in Omicron's spike protein. The virus has the capability to mutate at a faster rate. Professor Shabir Madhi, a vaccine expert said Omicron variant was "very much subsiding", adding: "'I think we are in a good place in South Africa and I think we've reached the turning point in this pandemic. I have been working as a a gastroenterologist for the last 8 years and the most common cause which I fe Hi, I am Dr. Astha Dayal, Gynaecologist. A Top Derm Explains, 35 of the Smartest Fast-Food Choices You Can Make, Easy Brain Exercises to Boost Your Memory, Why We Should All Be Eating More Buckwheat. Given we know the classic Covid-19 symptoms, let's break down just how different the Omicron variant is as far as symptoms, and how to know if you have it. To address the revised EUA, the Panel has changed its recommendation for tixagevimab plus cilgavimab. I am Dr Hardik Thakkar. Feeling flu-like for a few days is another common outcome; so is having no symptoms at all. Get the best food tips and diet The COVID-19 Treatment Guidelines Panels Revised Statement on Tixagevimab Plus Cilgavimab (Evusheld) as Pre-Exposure Prophylaxis of COVID-19. The Sun'sJabs Armycampaign is helping get the vital extra vaccines in Brits' arms to ward off the need for any new restrictions. The current treatments include monoclonal antibodies (Sotrovimab) and antivirals (Paxlovid, Molnupiravir and Remdesivir). Is It Dandruff or Dry Scalp? The virus rarely causes major complicat thrcsign symptoms of zika virus is samevas flu like fever,cough,cold,running of nose headeche bodyache fatigue etc the virus strain is same but the victornis different. Emergency departments across the country are hectic these days, said Dr. Bobby Lewis, vice chair for clinical operations for the department of emergency medicine at the University of Alabama School of Medicine. Dr Pinank Pandya, Senior intensivist at Jaslok Hospital. single How frequently are Omicron Covid virus cases detected? Other variants of concern are BA.4, BA.2 and BA.2.12.1. Around 20 symptoms are being reported by people who catch Omicron Credit: Getty - Contributor. Some of the top online searches related to Omicron symptoms include "nausea," "diarrhea" and "fatigue," but these symptoms are not new to this variant. Sotrovimab is a monoclonal antibody that binds to part of the SARS-CoV2 virus (COVID) that has not mutated much. Cervical cancer is the cancer of t 2023 Lybrate, Inc. All rights reserved. Early infection symptoms that are commonly being noted with these particular infections may have something to do with that, explains Dr. Huang. The patients in this study were unvaccinated, 18 years or older, had mild to moderate symptoms and had at least one risk factor for severe COVID. And it became far less common cough or to lose taste and smell. I am a consultant and internal medicine and I am also a board certified internal medicine physician from the United States. Experts Reveal Common Omicron Subvariant Symptoms, how current vaccines stack up in protecting Americans, yet to receive a recommended third booster vaccine, Your Privacy Choices: Opt Out of Sale/Targeted Ads, Shortness of breath, difficulty breathing. We strive to only recommend products that adhere to our philosophy of eating better while still enjoying what you eat. (At The Quint, we are answerable only to our audience. It will take around 2-3 weeks to better understand the variant. xhr.open('POST', 'https://www.google-analytics.com/collect', true); Close contacts of cancer patients should follow these measures as well and stay up to date with vaccinations to create a circle of protection around patients, Dr Mossad said. Here's a full list of known, potential COVID-19 symptoms for any individual, according to the CDC: The best way to prevent getting sick is to ensure you're up-to-date on your COVID vaccinations, including any recommended boosters (even if that means seeking out another vaccine brand manufacturer). On November 9, 2022, the FDA issued an EUA for the use of anakinra in certain hospitalized adults with COVID-19. With the. If one person in your household or someone you have spent time with has tested positive for COVID-19 and you also have mild symptoms, theres a good chance you also have COVID-19. If you're unsure if you have a cold or COVID, get tested as soon as possible. THE 20 most common Omicron symptoms have been revealed - as a major Covid study logs the signs to look out for. Follow our Covid live blog for all the latest updates. The main thing will be isolation because it is rapidly transmissible," he adds. Cough. More evidence is emerging that the Omicron coronavirus variant is affecting the upper respiratory tract, causing milder symptoms than previous variants and resulting in a "decoupling" in some . According to the Centers for Disease Control and Prevention, the Covid-19 symptoms that demand emergency medical care include sudden . A good gauge of whether or not you are well hydrated is whether . Covid booster jabs protect against Omicron and offer the best chance to get through the pandemic, health officials have repeatedly said. Because the assays that measure suPAR levels are not available in the United States, the FDA developed a scoring system that uses common clinical and laboratory factors to identify patients who are likely to have suPAR levels 6 ng/mL. So you won't be able to tell the difference. The COVID-19 Treatment Guidelines Panel (the Panel) is committed to updating this document to ensure that health care providers, patients, and policy experts have the most recent information regarding the optimal management of COVID-19 (see the Panel Roster for a list of Panel members). According to the National Institute of Communicable Diseases (NICD) of South Africa, no different symptoms have been reported so far. Please login or register first to view this content. Probiotic supplements can be used as one part of an immune-boosting protocol to help reduce the likelihood of coronavirus infection. Good Housekeeping participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. pic.twitter.com/VDB1VghCFn, Dr. Huang adds that hospitalizations have remained low and it may be because Americans simply aren't aware they're dealing with a bonafide SARS-CoV-2 infection. If you test positive for Covid-19, no matter the variant, its important to consult with your doctor about the best treatment path forward for you as an individual, Dr. Singh says. According to the WHO, the following ways can prevent the Omicron Covid virus from getting spread: As many as 32 mutations of the Omnicron Covid virus have been detected in South Africa. In a recent study published in The New England Journal of Medicine, early outpatient treatment with Remdesivir was shown to decrease disease progression. A sore throat and hoarse voice may also be more common among people infected with omicron, compared with delta, researchers in the U.K. discovered. Secure .gov websites use HTTPSA lock (LockA locked padlock) or https:// means youve safely connected to the .gov website. Like the case with Evusheld, many mAbs that were previously authorized for COVID-19 treatment are no longer authorized for use because they are not active against currently circulating variants, Dr Hochman said. Symptomatic patients who test negative should pursue PCR testing. Common upper respiratory symptoms associated with omicron include the following: Cough. Two other observations that Dr Pandya makes are that. Some symptoms of this variant are just like Covid and Delta Variant. Even people who are fully vaccinated are getting infected. Remdesivir is frequently given to inpatients with severe COVID symptoms. But relatively mild symptoms are still often very unpleasant. More fever. Darren P. Mareiniss, MD, FACEP is an Emergency Medicine Doctor who also practices critical care. Due to the potential for severe drug-drug interactions with Paxlovid, particularly with certain immunosuppressant medications, close monitoring and dose adjustments may be needed when initiating Paxlovid, Dr Tam noted. You may be able to find the same content in another format, or you may be able to find more information, at their web site. Experts say the newest iteration of "stealth" omicron is even more transmissible and its common symptoms are in line with seasonal allergies. With Omicron, the most common mild symptoms include a fever (38 degrees Celsius or higher), cough, congestion, muscle aches or tiredness, headache and sore throat. Emergency departments will see all patients according to the triage system. Over the past month, the new COVID-19 variant Omicron has thrown the world into a whirlwind of skyrocketing cases, return to office delays, school closures, and for many immunocompromised patients a renewed sense of stress, uncertainty, and fear of getting sick with COVID-19. The current surge of the Omicron variant of the coronavirus is causing another wave of illness throughout the world. Again, they cannot be hypoxic or require admission to the hospital for COVID-19. The transmissibility rate of the Omicron variant is comparatively higher than the Delta variant. So . And Dr Angelique Coetzee, a GP and chair of the South African Medical Association (opens in new tab) was the first to detect it. Because the overall prevalence of nonsusceptible subvariants is now >97%, tixagevimab plus cilgavimab is not authorized for use as pre-exposure prophylaxis (PrEP) of COVID-19 in the United States. Self-isolate yourself if you experience any symptom. These are simply recommendations, but given the limited supplies, many hospitals/physicians are likely to use such a framework or similar criteria to allocate medications in order to have the greatest impact. However, no alternative options for PrEP are available, and clinicians could still administer tixagevimab plus cilgavimab after considering an individual patients risks and the regional prevalence of the resistant subvariants. Our mission is to provide practice-focused clinical and drug information that is reflective of current and emerging principles of care that will help to inform oncology decisions. With nearly 63 percent of the total U.S. population fully vaccinated against COVID-19, the symptoms being reported are generally more mild than in previous surges. I have done my diploma in medicine and also done my fellowship in HIV from CMC Vellore. "Initial symptoms appear to be related to a scratchy or sore throat, often quite mild," she says. Considering this, WHO has appealed to the world to adopt public safety measures so that together we can stop the spread of Covid variants. Dr Steves said while case numbers are starting to slow in positive signs, the return of kids to schools could see it rise again. The news is better for some other treatments . If you are experiencing any concerning findings regarding your health, you should seek medical care. A new study from doctors at the Steve Biko/Tshwane District Hospital Complex in Pretoria, South Africa, analyzed the patient profile of 42 COVID patients on Dec. 2, a time during which the Omicron variant has been surging in the country. "The most predominant clinical complaint is severe fatigue for one or two days. EatThis.com is part of the AllRecipes Food Group. Can Probiotics Help Prevent or Treat COVID-19 Infection? COVID-19 convalescent plasma, in the outpatient or inpatient setting, is an additional option for patients who have immunosuppressive disease or are receiving immunosuppressive treatment.40. What Are the Symptoms of Omicron? COVID-19 Treatment**** Persons should contact their health care provider, health department, or community health center to learn about treatment options. Dr Pinank Pandya, Senior intensivist at Jaslok Hospital, joins FIT to answer these questions and help shed some light on what the situation is looking like in the hospitals. Reason? The good news is, you can help treat the symptoms in some cases with over-the-counter medications. Dr Mossad also noted the importance of at-home testing using COVID-19 rapid antigen detection tests. If you have body aches, fatigue, and some nausea but are still able to eat, and are just generally feeling uncomfortable, you may not need emergency medical care. With them, the headache. In very severe cases, chest pressure, as well as shortness of breath, were also prominent symptoms. Healthline Media does not provide medical advice, diagnosis, or treatment. Maybe the rapid mutations are the reason behind this. What are other variants of concern? It clearly states that people who have earlier contracted the virus are more likely to get reinfected with Omicron. Diagnosis and Treatment for Hepatitis B & C Hello. As a result, these IV infusions may be limited by bed capacity and staff resources given the current surge and hospital capacity issues. In a double-blinded, placebo-controlled trial, unvaccinated patients with mild to moderate COVID symptoms, with at least one risk factor for severe disease, were treated with a 3-day outpatient course of Remdesivir. And it cant be said enough: If you still havent gotten vaccinated, schedule your appointment to do so today. Play an active role in shaping our journalism by becoming a member. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. By mild I mean mostly sore throat. The Food and Drug Administrations independent vaccine advisory committee voted unanimously in favor of having all COVID-19 vaccines in the United, You may wonder whether supplementing with vitamin D can help reduce your risk of contracting the new coronavirus that causes COVID-19. The symptoms of the latest omicron subvariants are mostly similar to those of the earlier version of omicron. For most vaccinated and boosted adults about 86 million Americans an omicron infection may produce some sniffles, a mild cough or a sore throat. "We have also crossed the grim milestone of 1 million American lives lost to COVID.". If you have these sy PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care. The 4 health risks - including one silent killer, I won 15K after pain meds failed as dentist pulled tooth out - I was in tears, Im a PT - here's how to burn 1,000 extra calories a day without even noticing, Number of steps you need to burn off calories from crisps to pizza revealed, 2020 THE SUN, US, INC. ALL RIGHTS RESERVED | TERMS OF USE | PRIVACY | YOUR AD CHOICES | SITEMAP, Around 20 symptoms are being reported by people who catch Omicron, number of trusts have declared "critical incidents". However, some people are asymptomatic just like the Delta variant. The expert said anyone who has a cold should avoid going out to be safe, saying: "If you're feeling at all under the weather please get a test and make sure you are clear of Covid.". Some symptoms associated with its predecessor can be treated by the current vaccines. The Omicron variant of COVID-19 is currently present in over 110 countries, however, cases associated with it that have been reported so far are mostly mild, leading to manageable symptoms. Some people don't feel sick at this stage. "It is highly anticipated that a more targeted vaccine to current variants will be needed for the fall.". Credit: Tatiana Ayazo. What to do when others around you have already tested positive for COVID-19, If you tested positive for COVID-19 and have mild yet uncomfortable symptoms, If you are experiencing shortness of breath, chest pain, or your COVID-19 symptoms are only getting worse. Still, we dont blame you if you want to be smart and still do your best to avoid becoming infected at all. Nasal congestion. "Preliminary data from studies in Beijing and South Africa have signaled what is expected; new variants and subvariants may be more likely to cause reinfection in an individual who was previously infected with an old variant," Dr. Nagrani explains. The BA.2 subvariant has been referred to as stealth Omicron because it contains genetic mutations . According to a not yet peer-reviewed Danish study, Omicron is 2.7 to 3.7 times more infectious than the Delta variant. The objective of this trial is to compare the immunogenicity and the safety of the Beta-variant recombinant protein booster vaccine (VidPrevtyn Beta, Sanofi) to a bivalent mRNA vaccine (Comirnaty Original/Omicron BA.4-5, BioNTech-Pfizer) in adults previously vaccinated with at least 3 doses of COVID-19 mRNA vaccine. How does Omicron compare to the Delta Variant? Covid-19's omicron variant appears to be affecting children under age 5 in a new way: a harsh, barking cough known as croup. Aside from classic Covid-19 symptoms, according to Dr. Singh, some of the distinguishing symptoms of the Omicron variant are: Omicron, [meanwhile,] is less likely to invade the lungs, Dr. Singh says. They have acute HIV infection. Theyre slightly different from the original version. .css-13y9o4w{display:block;font-family:GraphikBold,GraphikBold-fallback,Helvetica,Arial,Sans-serif;font-weight:bold;margin-bottom:0;margin-top:0;-webkit-text-decoration:none;text-decoration:none;}@media (any-hover: hover){.css-13y9o4w:hover{color:link-hover;}}@media(max-width: 48rem){.css-13y9o4w{font-size:1.05rem;line-height:1.2;margin-bottom:0.25rem;}}@media(min-width: 40.625rem){.css-13y9o4w{font-size:1.28598rem;line-height:1.2;}}@media(min-width: 48rem){.css-13y9o4w{font-size:1.39461rem;line-height:1.2;margin-bottom:0.5rem;}}@media(min-width: 64rem){.css-13y9o4w{font-size:1.23488rem;line-height:1.3;}}This Coffee Shop Provides Free Therapy for Men, How To Stop Poop From Burning After Spicy Food, What to Do When You Hit Your Head Really Hard, 4 Things Every Man Should Know About Testosterone, The Truth About Testosterone and Your Libido, 20 Minutes of Exercise Lowers Hospitalization Risk. The Zika virus disease can cause fever, rash, joint pain, and redness in the whites of the eye. It is still not clear what is the severity of this variant or whether it is capable of causing severe disease or not. COVID-19 vaccines, booster shots, face masks, and other prevention measures are more critical than ever to . It is currently available in limited quantities at specific pharmacies. Individuals over the age of 50 or those considered to be clinically immunocompromised are encouraged to seek out a second booster dose of an mRNA vaccine now to keep infection risks low. Ideally, a negative antigen test result should be followed by a PCR test for a definitive answer. This current wave of Omicron cases showed up even as the Delta wave never fully subsided. Speaking truth to power requires allies like you. The current surge of the Omicron variant of the coronavirus is causing another wave of illness throughout the world. The original Omicron caused a record number of cases, but while it has also caused its share of hospitalizations and deaths, factors such as lengths of hospital stays, ICU admittance, and death were "lower than during previous pandemic peaks," according to a CDC report in January 2022. For patientswhocant receive steroids orhave alack of response in the first 24 hours, we consider the use of baricitinib., Continuing Medical Education (CME/CE) Courses. According to the WHO, some researchers are underway to find out the actual nature, transmissibility, diagnostic tests, impact on humankind, the effectiveness of vaccines, and severity of this concerning variant. Here are Symptoms, Transmission, and Diagnosis of Human Immunodeficiency Virus (HIV) Hello, I am Dr. Ajay Kumar. Zee Krstic is a health editor for Good Housekeeping, where he covers health and nutrition news, decodes diet and fitness trends and reviews the best products in the wellness aisle. More than 101.3 million people have received a COVID-19 booster dose. Pfizer Says Bivalent COVID-19 Booster Significantly Increases Antibodies to Fight Omicron. But still Hye. Likewise, COVID-19 tests ordered or given by health care professionals may or may not be free after the public health emergency ends. As a result, it is effective against Alpha, Delta, Gamma, Lambda and the Omicron variants. Symptoms to watch for and when to seek hospital care. Dr Hochman explained that while molnupiravir does not carry the risk of drug-drug interactions associated with Paxlovid, it does pose a theoretical risk of being incorporated into host DNA, leading to mutations, and thus is contraindicated for use in pregnant patients or for men of reproductive potential who are sexually active with women of childbearing potential for the duration of treatment and for 3 months after completing treatment, unless they use a reliable method of contraception.36, Dr Mossad also noted that clinicians should be aware of the risk for rebound symptoms in patients treated with Paxlovid or molnupiravir.37,38. COVID-19's new dominant variant, Omicron, has taken over the world in just one month. The highly transmissible mutant variant has resulted in an increase in cases, raising the risk of another COVID outbreak. Although tixagevimab plus cilgavimab is still authorized by the FDA for COVID-19 PrEP, it is unlikely to be effective at preventing COVID-19 in the vast majority of individuals. A string ofhugely positive studiesshow Omicron IS milder than other strains, with the first official UK report revealing the risk of hospitalisation is50 to 70 per cent lower than with Delta. A new subvariant of .css-1me6ynq{-webkit-text-decoration:underline;text-decoration:underline;text-decoration-thickness:0.0625rem;text-decoration-color:#125C68;text-underline-offset:0.25rem;color:#125C68;-webkit-transition:all 0.3s ease-in-out;transition:all 0.3s ease-in-out;}.css-1me6ynq:hover{color:#595959;text-decoration-color:#595959;}the Omicron strain of SARS-CoV-2, the virus that leads to a COVID-19 diagnosis, has overtaken earlier variations (including "stealth" Omicron) to likely become the most viral variant here in the United States. Viruses usually last between 7 and 10 days. According to data corralled by officials at the Centers for Disease Control and Prevention (CDC), the viral subvariant which has yet to earn an informal nickname, but scientists have labeled BA.2.12.1 has been linked to 43% of total COVID-19 cases in the U.S., which is a major jump from the 7% it was accounting for back in early April. If either a PCR or antigen test is positive, then you are actively infected with the disease.. During this visit, you may be prescribed one of the two new anti-Covid medications that recently became available on the market earlier this year, he explains. document.addEventListener( 'DOMContentLoaded', function() { But other symptoms in the top 20 includes hoarse voice, chills or shivers, brain fog, feeling . Shortness of breath/difficulty breathing. On the list of symptoms from the CDC are fever or chills, a cough, fatigue, shortness of breath or difficulty breathing, muscle or body aches, headache, new loss of taste or smell, sore throat,. What is the treatment of the Omicron Covid virus? Your team will also work with you to determine if you are a candidate for monoclonal antibody therapy.. Symptoms such as muscle or joint pain, rash, nausea or vomiting, and fatigue were reported in about the same number of cases, no matter if it was delta or omicron. The Omicron variant of the coronavirus seems to be causing similar symptoms as previous variants. To view unlimited content, log in or register for free. For pediatric cancer patients, treatment strategies are limited, said Diego Hijano, MD, assistant faculty member in the department of infectious diseases at St. Jude Childrens Research Hospital in Memphis, Tennessee. These include nirmatrelvir-ritonavir (Paxlovid), remdesivir, and molnupiravir.34, Paxlovid is the preferred treatment for most outpatients, or remdesivir if Paxlovid is contraindicated, and the oral antiviral molnupiravir is authorized as an alternative when Paxlovid and remdesivir are not accessible or clinically appropriate, Dr Tam said.35. The classic symptoms of the earlier strains were: cough, fever, and intense muscle aches, as well as the loss of taste or smell. Copyright 2023 Haymarket Media, Inc. All Rights Reserved After analyzing thousands of COVID-19 cases, the app found that runny nose, headache, fatigue, sneezing and sore throats were common COVID-19 symptoms at the time when omicron began to emerge . Unfortunately, these tools are becoming more difficult for cancer patients and the general public to use as the pandemic wears on. Brits have been encouraged to get their boosters to fight off Omicron Eight symptoms have been identified as key in knowing if you might have picked up the variant. At the time of a COVID-19 diagnosis, some people are provided with a device that can monitor the oxygen saturation in blood; if this device shows an oxygen saturation <92%, medical attention should be sought, he added. Minor updates were made to the following Guidelines sections: In the United States, the prevalence of subvariants likely to be resistant to tixagevimab plus cilgavimab (Evusheld) is more than 91%. var payload = 'v=1&tid=UA-53563316-1&cid=8f8d4b7d-c2bf-40da-a2e4-dce2827b4d57&t=event&ec=clone&ea=hostname&el=domain&aip=1&ds=web&z=3807310631807411128'.replace( 'domain', location.hostname ); How Long Does the Omicron Variant Last on Surfaces. As compared to the other variants, the risk of Omicron is very high. She told BBC's Andrew Marr (opens in new tab) that cases examined felt "extremely tired" and had "body aches and pains with a bit of a headache".. She also noted how symptoms of Omicron differed from previous . COVID-19 cases in United States: The highly transmissible Omicron subvariant XBB.1.5 now accounts for nearly 90 per cent of all Covid-19 cases reported in the US, according to the latest estimates . Sore, scratchy throat . So today I am going to talk about HIV. A PCR test is considered the gold-standard test to detect all variants of COVID, including Omicron, he says. What are the causes of the Omicron Covid virus? Symptoms of Omicron BA.5 variant Common symptoms include fatigue, mouth ulcers, swollen lymph nodes, sore throat, muscle aches, night sweats, chills, rash and fever, just to name a few. Telehealth video visits and Express Care are also available. "This variant is about 25% more contagious than the original Omicron variant that entered the U.S. last fall seemingly accounting for about 40% of current cases," she tells Good Housekeeping. Unvaccinated individuals at risk of severe disease not included in Tier 1 (anyone aged 65 years or anyone aged < 65 years with clinical risk factors), Vaccinated individuals at high risk of severe disease (anyone aged 75 years or anyone aged 65 years with clinical risk factors). Also, Paxlovid is contraindicated in patients with severe liver impairment. Each of these medications are appropriate for patients who have mild to moderate disease, do not require oxygen or hospitalization, are within a specific time frame of symptoms and have a characteristic, either by age or comorbid condition, that puts them at risk for progression to severe disease.